| Prime Minister | Party | Years in office | Brief description |
| Harold Macmillan | Conservative | 1957-1963 | |
| Alec Douglas-Home | Conservative | 1963-1964 | |
| Harold Wilson | Labour | 1964-1970, 1974-1976 | |
| Ted Heath | Conservative | 1970-1974 | |
| James Callaghan | Labour | 1976-1979 | |
| Margaret Thatcher | Conservative | 1979-1990 | |
| John Major | Conservative | 1990-1997 | |
| Tony Blair | Labour | 1997-2007 | |
| Gordon Brown | Labour | 2007-2010 | |
| David Cameron | Conservative | 2010-2016 | |
| Theresa May | Conservative | 2016-2019 | |
| Boris Johnson | Conservative | 2019-2022 | |
| Liz Truss | Conservative | 2022 | |
| Rishi Sunak | Conservative | 2022- | |